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Results indicated thatexposure to tirzepatide remained consistent across all groups, and there were no significant impacts on its pharmacokinetics.Reported adverse events were mostly mild and related to the gastrointestinal system in the renal impairment groups [81]
Certain genetic profiles may be associated with greater nausea sensitivity early in treatment
It is administered sublingually (under the tongue) where it is easily absorbed through the mucous membrane
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While modest heart rate increases are expected and generally well-tolerated, certain symptoms warrant prompt evaluation
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