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Prog Biophys Mol Biol 120(13):199209

"Genetics are often the primary driver of premature graying but environment and lifestyle factors also play a role and can accelerate it." While optimizing glutathione and antioxidant levels can help, Lee said it won't compensate for systemic poor health including smoking, high alcohol intake and processed food-heavy diets

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It acts through melanocortin receptors, especially MC1R, which helps melanocytes make eumelanin, the type of pigment linked to stronger UV protection

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