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Some researchers notice reduced food noise (the constant background thinking about food) within the first week

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Zuber V, Grinberg NF, Gill D, et al

Clinical trial data from the SURMOUNT-1 study demonstrated that patients achieved maximum weight loss at approximately 72 weeks (18 months), with average reductions of 15.0% (5 mg), 19.5% (10 mg), and 20.9% (15 mg) of initial body weight

1 Recently, GLP-1s have emerged as alternatives due to their effects on weight reduction and glycemic control

They fall steadily with age and are depleted further by chronic stress, alcohol, poor sleep, intense exercise, processed diets, environmental pollution and particularly relevant in Dubai sustained UV exposure