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[PubMed: 23400093] 41
It is produced in the body from the amino acids L-lysine and L-methionine and also occurs naturally in meat, cereals, nuts, mushrooms, fruit, and vegetables, making it part of the normal diet
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(Given the potential long-term consequences of NMOSD relapses, the company could not ethically include a direct placebo arm in its Phase III trial.) Ultomiris was well-tolerated overall, and most treatment-emergent events were mild or moderate in severity, according to AstraZeneca
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