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Semaglutide dosing typically begins at 0.25 mg weekly and escalates over 412 weeks, with many patients reaching 1 mg as an intermediate milestone

Gut-derived peptide hormone analogues and potential treatment of bone disorders in obesity and diabetes mellitus

This positions it well for patient convenience and adherence

Outcomes and objectives The primary objective was to compare the efficacy of 68 weeks of subcutaneous semaglutide 2.4 mg weekly versus placebo administration, as an adjunct to diet and exercise, on %WL in participants with less than 20% weight loss after primary GB or SG at the end of 68 weeks of treatment

It also controls bowel movements

10.1016/j.ejca.2012.08.019 6