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Pooled analyses of phase III studies of ADS-5102 (amantadine) extended-release capsules for dyskinesia in Parkinsons disease

Introduction Thiamine is a critical and rate-limiting cofactor for many enzymes, including those acting at entry points and critical junctions for glucose, fatty acid, and amino acid pathways

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J., Strickland, P

It features a heterodifunctional molecule integrating two crucial ligands: one targeting and binding to the protein of interest, and another engaging with an E3 ligase, a pivotal element within the ubiquitin-proteasome system tasked with marking proteins for degradation (Zeng et al., 2021)

Grcarma: A fully automated task-oriented interface for the analysis of molecular dynamics trajectories