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Adding to the complexity, interferon-gamma (IFNG/IFN-), which is released from CD8 + T cells, downregulates the expression of SLC7A11, effectively promoting ferroptosis induction in HT-1080 and B16 cancer cells [208]

Recently, a biased GLP-1R agonist with reduced -arrestin-1 recruitment was described as poorly insulinotropic in vivo 61 , contrasting with our observations for exendin-phe1 and several other analogs

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PD-L1 expression is mainly regulated by interferon gamma associated with JAK-STAT pathway in gastric cancer

The results in aged mice were particularly striking