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We are literally just scratching the surface of global [obesity] treatment here, Chair and CEO of Eli Lilly David Ricks said in an Oct

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A landmark study examined electronic health records from multiple healthcare systems and identified a statistically significant elevation in the incidence of nonarteritic anterior ischemic optic neuropathy among patients prescribed these medications compared to those receiving alternative diabetes or weight management therapies

People who might benefit the most from switching from semaglutide to tirzepatide include those who: Havent lost as much weight as they hoped to on semaglutide, or have run into a weight loss plateau Havent reached their target HbA1c levels on semaglutide, or are hoping for further reductions Have another health condition that only tirzepatide is FDA-approved to treat, such as obstructive sleep apnea If semaglutide hasnt been working well for you, it might be worth switching to tirzepatide

It does, however, establish that less than maximum dosing can preserve some of the benefit, while also demonstrating a dose-response more efficacy with higher dose