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In this context, targeting QA, or the enzymatic steps that govern the balance of KP metabolites, may represent a more tractable therapeutic strategy, allowing attenuation of NMDAR-driven excitotoxicity without disrupting 7nAChR-dependent cognitive processes

Expression of Indian hedgehog, parathyroid hormone-related protein, and their receptors in the postnatal growth plate of the rat: evidence for a locally acting growth restraining feedback loop after birth