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Sometimes considered when brain fog/headache or inflammatory sensitivity are prominent alongside mast-cell symptoms

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In addition to its participation in the WWC, ascorbate is also required for the regeneration of lipid-soluble antioxidants, particularly tocopherols and tocotrienols (vitamin E), which protect the polyunsaturated fatty acids in the thylakoid membranes from oxidation to chromanoxyl radicals by singlet oxygen

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Forrest JA, Clements JA, Prescott LF (1982) Clinical pharmacokinetics of paracetamol