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Nigam SK, Wu W, Bush KT, Hoenig MP, Blantz RC, Bhatnagar V (2015) Handling of drugs, metabolites, and uremic toxins by kidney proximal tubule drug transporters

The "Pro" label signals that a healthcare provider is involved in the recommendation, which adds a layer of clinical oversight

More serious side effects include lactic acidosis, which is, however, very rare and is reduced by avoiding its use in patients with severe renal and liver dysfunction (9, 1115)

Vitamin B12 deficiency causes tiredness, weakness, constipation, loss of appetite, weight loss, and megaloblastic anemia

Sebaceous gland, hair shaft, and epidermal barrier abnormalities in keratosis pilaris with and without filaggrin deficiency

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