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[9] Pharmacodynamic Interaction Assessment A pharmacodynamic (PD) interaction occurs when two agents affect the same physiological target or downstream pathway, producing additive, synergistic, or antagonistic effects even without altering each other's concentrations

8.4 M GSSG [27]), the E GSH for the Plasmodium trophozoite cytosol at pH 7.2 and 37C has so far only been roughly estimated [22]