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This allows it to reach room temperature, which can help reduce discomfort during cold injections

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Although the residues at the N-terminal position may have a major impact by inhibiting DPP4, the authors pointed out that the C-terminal amino acid also affects the potency of DPP4 because it is involved in the interaction with the enzyme (Reference Lan, Ito and Ohno95)

Non-steroidal anti-inflammatory drugs (NSAIDs) should be avoided where possible as they may worsen dyspepsia

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GLP-1 agonists are medications that mimic the effect of this hormone and, on average, lower hemoglobin A1C by 0.8% to 1.5%