Yang Q, Wang M, Wang H, Ren C, Li Y
S., Jo, I., Oh, G
Frequently Asked Questions How quickly will I notice appetite changes on GLP-1 medication
Research shows these medications reduce the activation of the NLRP3 inflammasome in brain microglia, suppress pro-inflammatory cytokines including TNF-alpha, IL-1 beta, and IL-6 in the hippocampus and spinal cord, inhibit microglial activation in pain-processing centers, and reduce oxidative stress that contributes to nerve damage
To be more precise, the research only showed a temporary increase of a substance called Trimethylamine N-oxide (TMAO), sometimes associated with heart disease, but was never actually proven to be the cause
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