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The trial results showed that after a 68-week treatment period, the oral semaglutide group achieved a significant weight reduction compared to the placebo group, with a 17.4% decrease in body weight versus 1.8% in the placebo group
Unfortunately, despite its high prevalence, a large number of MASLD cases remain undiagnosed, often leading to a diagnosis of cryptogenic cirrhosis, where MASH is the underlying condition once other etiological factors for chronic liver disease, such as alcohol abuse, viral hepatitis, autoimmune disorders, and other metabolic diseases, have been excluded [23]
Cardiovascular effects of the DPP-4 inhibitors