In contrast, gradual weight loss allows the body to adjust to changes more effectively, reducing the risk of negative health consequences
But individual response varies enormously
Collaborative Study Group
Patients with BMI 25 (Indian standard), or BMI 23 to 27 with metabolic risk factors such as prediabetes, high waist circumference, PCOS, or fatty liver
For patients considering their options: if oxidative stress is clinically evident (ask your physician about inflammatory markers like hsCRP, liver enzymes, or oxidised LDL), glutathione or NAC supplementation is reasonable adjunctive support
Pajares MA, Duran C, Corrales F, Pliego MM, Mato JM: Modulation of Rat Liver S-Adenosylmethionine Synthetase Activity by Glutathione