Common side effects include: Constipation Decreased appetite Diarrhea Nausea Vomiting Researchers reported that these side effects were usually mild to moderate and most commonly occurred during the dose-escalation phase of treatment
In October, Found Health and Hims & Hers entered the fray
The side effects observed were [31]: Nausea (24% of participants) Diarrhea (21%) Vomiting (14%) Constipation (8%) Dyspepsia (7%) Injection site reactions (3%) Cholelithiasis (less than 1%) Pancreatitis (less than 1%) Gastrointestinal side effects were the most common reason for discontinuation and their severity varied from mild to moderate
After 20-24 weeks, many users transition to maintenance mode, using lower doses to sustain achieved losses rather than pushing for continued reduction
Understanding liver enzymes diabetes risk is becoming increasingly important because these commonly ordered blood tests may help identify people Read More Beyond the FIB-4: Why Diabetes Care Is Becoming a Hepatology-Endocrinology Partnership May 20, 2026 Articles, Diabetes, Gastroenterology, Obesity, Obesity, Type 2 Diabetes, Type 2 Diabetes 1,764 views Screening for fatty liver disease in patients with diabetes is no longer limited to identifying elevated liver enzymes or calculating a fibrosis score during an annual visit
Nonetheless, these severe side effects were also present in some people who took GLP-1s and tirzepatide for weight loss and were not suffering from type 2 diabetes
