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Following IcoSema administration, the competition for albumin binding between icodec and semaglutide results in a greater fraction of free, unbound semaglutide at the injection site

While previous studies have shown benefits of liraglutide in this group, BARI-STEP is the first randomised controlled trial of semaglutide in patients following bariatric surgery

[Google Scholar] 55.Hu W., Zhang L., Lin F., Lei J., Zhou M., Xu A

Treatment starts at 0.25 mg weekly and increases every four weeks through 0.5 mg, 1.0 mg, and 1.7 mg before reaching the maintenance dose of 2.4 mg per week

Ensure the tablet is positioned for maximum contact with the mucous membranes