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At age 50, everyone, regardless of diet should start supplementing with B12-fortified foods or supplements but over age 65 only high-dose daily supplements may suffice

These results suggest that sublingual and oral B12 supplementation may serve as viable alternatives to IM injections, particularly in clinical settings where frequent intramuscular administration is impractical or resource intensive

doi:10.3945/ajcn.111.020230

With a 5mg vial reconstituted at 2mL (2.5mg/mL), here is how the math works across the full titration: At the starting dose, a single 5mg vial lasts nearly five months

If you know your protocol will reach 7.5mg or higher, consider the 1ml reconstitution from the start

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