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Pancreatic beta cell dedifferentiation as a mechanism of diabetic beta cell failure

Isolation and characterization of peptide YY (PYY), a candidate gut hormone that inhibits pancreatic exocrine secretion

The medication improves blood sugar, cholesterol, blood pressure, and inflammation

This study compared thousands of patients treated in real clinics, which is powerful, but it wasnt a randomized trialso results dont prove cause-and-effect for every person

Management focuses on dietary modifications, prokinetic medications, antiemetics, and in severe cases, surgical interventions or gastric electrical stimulation (though the latter is limited to specialised centres for selected refractory cases)

A proteomic signature was identified that robustly predicted semaglutide treatment status