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10.1172/JCI59755 69 MengX.AnX.ZhouL.FuB.JiaL

Molybdenum cofactor deficiency Type A is due to mutations in the MOCS1 gene, while Type B deficiency is caused by mutations in MOCS2

Cellular and molecular consequences Elevated oxidative stress and inflammation damage nerve cells

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Chronic ethanol exposure caused exacerbated neuroinflammatory impairments in APP/PS1 mice To further explore the underlying mechanisms of ethanol-induced neuroinflammatory impairments, we firstly detected the protein expression level of crucial inflammatory factors, including NLRP3 and TNF-