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Of note is also that the supplementation with folic acid at doses higher than 1000 g/d was negatively associated with global verbal scores in children (Reference Valera-Gran, Navarrete-Muoz and Garcia de la Hera121)

For example, studies show improvements in running speed, increased maximal oxygen uptake, and decreases in average oxygen consumption, heart rate, and lactic acid

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INTRODUCTION In 1970, Laugier and Hunziker reported five cases of unusual acquired macular hyperpigmentation on the lips and oral mucosa, and two of these patients displayed longitudinal pigmented streaks on the nails[1]