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Treating bacterial overgrowth can help restore balance to the gut microbiome, potentially reducing histamine production and improving the bodys ability to process histamine

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NAD+ acts as an essential cofactor for key cellular antioxidant enzymes, enabling them to neutralize damaging free radicals

As an outcome, metformin treatment restores spine density, surface GluA1 trafficking, long-term potentiation expression, and spatial memory (Wang et al., 2020c)