[DOI] [PMC free article] [PubMed] [Google Scholar] 136.Speese S.D., Budnik V
Equines have a well-documented somatotropic axis, meaning the pathways that regulate growth hormone (GH) release, liver-derived IGF-1 production, and downstream anabolic signaling are well-characterized enough to draw meaningful comparisons to human physiology
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In addition, other strategies have also been developed to enhance the lymph node-targeted vaccination, including the pullulan nanogel system (240), synthetic vaccine nanoparticles (239), LN-targeted lipid nanoparticles (242, 245), and LN-targeted immunization formulation (244, 246, 247)