However, because it improves insulin sensitivity, diabetes medications may need to be adjusted
You're a strong candidate for B12 injections if you experience any of the following: Persistent fatigue that sleep doesn't fix Brain fog, forgetfulness, or trouble concentrating Low mood, anxiety, or stress that feels disproportionate to what's happening Weight gain or difficulty losing weight despite consistent effort Tingling, numbness, or weakness in hands or feet (signs of B12-related neuropathy) Frequent colds, slow healing, or post-COVID fatigue A plant-based, vegetarian, or vegan diet Age 50 or older (B12 absorption naturally declines with age) A history of gastric bypass, Crohn's disease, celiac disease, or chronic acid reflux Long-term use of metformin (for diabetes), proton pump inhibitors (Prilosec, Nexium), or H2 blockers (Pepcid, Zantac) An MTHFR gene variant or known methylation issue A history of B12 deficiency, pernicious anemia, or low folate Hormonal shifts: perimenopause, menopause, postpartum If you fit one or more of these, a vitamin B12 shot is one of the lowest-risk, fastest-acting interventions available
Roles of serotonin in cravings and dependence include regulating reward responses, influencing impulsivity, and affecting compulsive behaviors related to substance use
Have Digestive Concerns: Great for those with absorption issues that limit oral supplement effectiveness
Correro AN, Nielson KA
Reduced glutathione: a radioprotector or a modulator of DNA-repair activity
