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The environmental sensor AHR protects from inflammatory damage by maintaining intestinal stem cell homeostasis and barrier integrity

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However, the basis for the increased lactate and pyruvate, in some instances, may relate to non-mitochondrial processes such as glycolysis as is suggested by the absence of increased alanine and TCA intermediates noted in some other biomarker clusters (Figure 5, group 4)

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Fertility and pregnancy complications : MTHFR polymorphisms have been linked to recurrent miscarriage, neural tube defects, and poor pregnancy outcomes [7]

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