Many patients experience a mild, temporary flush or warmth , which is a good sign the NAD+ is working
Discontinue use if irritation, redness, or rash occurs
Physiological oral mucosal melanin hyperpigmentation is very common in Blacks, in general is more frequent in darker-skinned than in lighter-skinned persons regardless of their race/ethnicity, and is most probably caused by genetically determined metabolic hyperactivity of oral melanocytes
S-sulfhydration: a cysteine posttranslational modification in plant systems
Many patients notice improvement in recovery over a few weeks
Remember, esters are weaker acylating reagents than either anhydrides or acyl halides, as noted earlier