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Semaglutide, a GLP-1 receptor agonist , is FDA-approved not only for type 2 diabetes but also for chronic weight management in adults who meet specific criteria

Recent clinical trials have shown that dual and triple agonists targeting these pathways can lead to superior reductions in body weight and liver fat compared to GLP-1R mono-agonists, with a comparable safety profile [16,17,18,19,20,21,22]

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Study limitations included a lack of imaging at follow-up and a lack of assessment of metabolic and inflammatory markers

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8 Studies have also shown semaglutide to be superior to some other weight-loss agents