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European Medicines Agency (EMA) Updates For patients in Europe, access to new medications is governed by the European Medicines Agency (EMA)

Viking Therapeutics Sector: Dual and triple agonists for obesity, metabolic, and liver disease HQ: San Diego, CA Year Founded: 2012 Origin Story: The company built its pipeline around small molecule and peptide candidates licensed from academic and pharma sources, eventually advancing VK2735, a dual GLP-1/GIP receptor agonist designed to be the first such therapy available in both oral and injectable formulations

Deane AM, Chapman MJ, Horowitz M

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Exendin-4 ameliorates high glucose-induced fibrosis by inhibiting the secretion of miR-192 from injured renal tubular epithelial cells

Thus we proposed the central idea of our commentary: Chronic glucagon suppression may shift amino-acid handling toward muscle proteolysis, creating a silent but progressive erosion of muscle reserve