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I bring this up because I've read that B12 is known to raise histamine levels, injections in particular

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Oral Oncol 48(6):500506 Hall C et al (2017) Inhibition of the apelin/apelin receptor axis decreases cholangiocarcinoma growth

This article will attempt to provide some clarification on these issues surrounding vitamin B12

Human umbilical vein endothelial cells (HUVECs) culture HUVECs purchased from BCRC (Hsinchu, Taiwan, ROC) were grown in M199 medium supplemented with 16% fetal bovine serum and 20% EGM-2 (Clonetics, USA)

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