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MPTP is an alipophilic prototoxin that rapidly crosses the blood-brain barrier and damage dopaminergic neurons due to the selective uptake of the active metabolite MPP + via the dopamine transporter [80]

Biochem Genet

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Carnitine is a key metabolite in the transport of fatty acids into the mitochondria - the power plants of the cells - where they are used to generate energy by means of -oxidation