Efficacy and safety of once-weekly semaglutide versus once-daily sitagliptin as add-on to metformin in patients with type 2 diabetes in sustain China: A 30-week, double-blind, phase 3a, randomized trial
Zepbound (tirzepatide) has helped millions achieve meaningful weight loss, but some patients report muscle or joint discomfort during the first few weeks of treatment
We therefore hypothesise that the GLP-1R-dependent phosphorylation of MIC19 at ERMCSs might not only highlight a direct role for the receptor in the control of mitochondrial dynamics, but also regulate lipid precursor transfer across ERMCSs to sustain mitochondrial turnover
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Weghuber D, Barrett T, Barrientos-Prez M, Gies I, Hesse D, Jeppesen OK, Kelly AS, Mastrandrea LD, Srrig R, Silva Arslanian 1