Compounded semaglutide side effects Common and serious side effects of semaglutide include: Common side effects The most common side effects of compounded semaglutide include: Nausea Abdominal discomfort Stomach problems Constipation Vomiting Diarrhea Serious side effects Serious side effects of compounded semaglutide can include the following: Severe stomach problems Changes in vision (due to diabetic retinopathy) Acute pancreatitis Gallbladder problems Hypersensitivity/allergic reaction Hypoglycemia (low blood sugar levels) Mood and behavioral changes Suicidal ideation Acute kidney injury Increased risk of aspiration in anesthesia and sedation The mild side effects of compounded semaglutide usually subside over time
These are generally mild to moderate and dose-related
Lower insulin levels and blood glucose reduce the chance of damage to blood vessels, eyes, joints, and more
Caan BJ, Cespedes Feliciano EM, Prado CM, et al
A family or personal history of melanoma, fair skin, red hair, and freckles represent additional risk factors that signal the need for especially diligent photoprotection and (particularly after puberty) periodic total body skin examinations
Public data were obtained from UniProt ( and from the National Center for Biotechnology Information ( accession numbers are provided in the Article or in Supplementary Datasets 1, 2, 3 and 5)