The ratio of GSH to GSSG within cells is often used as a marker for cellular oxidative stress, with a higher ratio indicating a more reduced (and less stressed) cellular environment
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In light of the data generated in this study, a more complete pharmacokinetic investigation designed to quantify the magnitude and duration of increase in GSH is warranted
Maria Dorotia Borges-Santos, Fernando Moreto, Paulo Camara Pereira, Yong-Ming Yu - Plasma glutathione of HIV+ patients responded positively and differently to dietary supplementation with cysteine or glutamine - Nutrition - Jul 2012
Glutathione is the body's primary intracellular antioxidant it directly neutralizes free radicals, supports liver detoxification, and is studied for skin brightening via melanin inhibition
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