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Melatonin inhibits the NF-B signaling pathway in TE-1 esophageal cancer cells, which decreases expression of MMP-9, a key enzyme in mediating cancer invasion and metastasis, leading to the suppressed migration and invasion of esophageal cancer cells [145]

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What Does This Mean For Operators

Dose Adjustments : Based on your blood pressure readings, the dose may be increased by 5-10 mg every few weeks until the desired blood pressure is achieved