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Targeting ferroptosis in pancreatic cancer: a double-edged sword

TakaradaTOguraMNakamichiNKakudaTNakazatoRKokuboHet alUpregulation of Slc38a1 gene along with promotion of neurosphere growth and subsequent neuronal specification in undifferentiated neural progenitor cells exposed to theanine

Int J Environ Res Public Health 11(6):56285639

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GO analysis showed that caffeine was involved in the biological processes of inflammation (neutrophil migration, regulation of MAP kinase activity, immune system process, natural killer cell degranulation, etc.), metabolism (response to lipid, glycosphingolipid metabolic process, lipid storage, etc.), and fibrosis (collagen receptor activity, etc.) (Figures 7E,G)

The mechanisms underpinning their effects on brain functioning are not fully understood, but the general consensus attributes their benefit to antioxidant capabilities [50]