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In a mouse model of liver fibrosis, zinc supplementation significantly suppressed fibrosis and inflammation, reduced collagen deposition, and decreased macrophage infiltration, together with inhibiting hepatic stellate cells

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The theory suggests these peptides may influence gene expression through epigenetic mechanisms, though the precise molecular interactions remain an area of ongoing investigation

Pain associated with inflammation has been ascribed to increased excitability of sensory neurons in the dorsal root ganglia (DRGs) 2

Larbig et al