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doi: 10.1038/s41598-020-71847-5 147 SantosSCFortesGACamargoLTCamargoAJFerriPH

The hair loss is typically telogen effluvium (stress-related shedding) rather than permanent, and usually resolves as weight stabilizes

Other reported side effects include injection site reactions and hypoglycaemia (particularly when used with insulin or sulphonylureas)

The LEAN-PREP study (NCT enrolling 2025) is the first, with results expected 2026-2027

Hydroxocobalamin and cyanocobalamin are both forms of Vitamin B12, but hydroxocobalamin stays in the body longer