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However, all gastrointestinal adverse events were mild in severity and none led to treatment discontinuation

Slowed gastric emptying, changes in transit time, and altered food composition create an environment where beneficial bacterial populations can decline while less desirable strains flourish

The new study was published Monday in the Annals of Internal Medicine

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SCALE OF IMPACT These significant advancements related to the GLP-1 endocrine process have laid the foundation for powerful therapies for Type 2 diabetes, obesity and short bowel syndrome, impacting over 100 million people with type 2 diabetes, more than 1 billion individuals with obesity, and over 3 million with short bowel syndrome

Curr Opin Endocrinol Diabetes Obes 27:215224 Stancill JS, Corbett JA (2021) The role of thioredoxin/peroxiredoxin in the -cell defense against oxidative damage