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Regul Pept (2001) 6:816

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Derived from the proglucagon gene, oxyntomodulin acts as a dual agonist at GLP-1 and glucagon receptors, promoting satiety and increasing energy expenditure ( The subsequent clinical success of engineered dual and triple incretin agonists has reframed these concerns

Although that may not seem like a lot, it translates to about 7.6 million fewer adults with obesity