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Discovered by de Rey-Paihade in 1888, it was termed as Philothion meaning love of sulfur in Greek

The progressive nature of T2DM in the deterioration of pancreatic -cell function was such that after 3 years, approximately 50% of patients could attain glycosylated hemoglobin (HbA1c) below 7% with monotherapy, and by 9 years, this declined to approximately 25% [1]

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Architectural role of mitochondrial transcription factor A in maintenance of human mitochondrial DNA