Taken together, these preclinical and clinical findings imply that the GLP-1 pathway plays a role in the complex mechanisms regulating alcohol and drug consumption patterns, unveiling a novel aspect of addiction medicine
Similar to GIP, the stimulatory effects of GLP-1 on insulin expression and secretion were observed in the presence of high (450 mg/dL) but not normal (99 mg/dL) concentrations of glucose in the cultured cells, indicating the glucose-dependent insulinotropic effect of GLP-1 (117)
Disrupted dynamics of F-actin and insulin granule fusion in INS-1 832/13 beta-cells exposed to glucotoxicity: partial restoration by glucagon-like peptide 1
Consider LLLT three to four times per week
They were also asked about GLP-RA use, including the specific drug, reasons for use, duration, side effects, and expected period of future use
Microdosing means using well-below-standard starting doses of a GLP1 agonist to gain metabolic and neurologic benefits while minimizing side effects