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Injecting cold medication directly from the refrigerator is a common cause of injection site discomfort and can trigger localised reactions

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Important safety considerations include a boxed warning for thyroid C-cell tumors, contraindication in patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2, and precautions regarding pregnancy (not recommended), reduced oral contraceptive effectiveness, and risks of pancreatitis, gallbladder disease, and acute kidney injury

In vivo examination of aluminum neurotoxicity has demonstrated that healthy mice treated with aluminum hydroxide display significant motor deficits and develop pathological features similar to those observed in ALS [62]

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