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Since a 1961 report by Paul O'Hollaren, MD, of Shadel Hospital in Seattle, Washington, NAD+ IV infusion has been widely utilized for the treatment of addiction (18-20)
Urology 133 , 7883 (2019)
The recommended dose of general health is to start out with 0.1ml (20mg NAD+) and, as desired, slowly ramp up to 0.4ml (100mg NAD+) 1-3 times per week
Furthermore, PKA activation is known to inhibit AMPK in GIP receptor and GLP- 1 receptor signaling, which results in the transfer of TORC2 into the nucleus [66]
Human data is extremely limited: ~30 subjects across all published studies
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