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NAD+ is a critical coenzyme involved in hundreds of enzymatic reactions including glycolysis, the citric acid cycle, and oxidative phosphorylation, as well as serving as a substrate for NAD+-consuming enzymes including sirtuins, PARPs, and CD38

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The active region is less than 10% of the entire human growth hormone peptide

A multi-target approach addresses more of these threats than any single compound

a case-controlled study