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MOTS-c has a plasma half-life of approximately 2 hours, but its metabolic effects persist for 68 hours due to downstream signalling cascades
Similarly, lentivirus-mediated c-MET gene silencing or c-MET inhibition with EMD1214063 reduced spherogenicity, but none of that was seen in T-269 cells (Fig
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The findings indicated that compound 7 had a superior cardiovascular profile compared to celecoxib
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