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Baseline characteristics among the three groups were well-matched for age, gender, body mass index, duration since diagnosis, prior use of any therapies (DMARDs, biologics, steroids) and clinical scores indicating disease activity

The present study hence focused on compounds, already in clinical use, with the potential to activate the Nrf2 stress response pathway

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J Cell Biochem 120:94099420 Maguire MJ, Hemming K, Hutton JL, Marson AG (2008) Reporting and analysis of open-label extension studies of anti-epileptic drugs

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Thereby, it may achieve more precise and effective treatment outcomes in the therapy of metabolic diseases such as type 2 diabetes and obesity