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Transfection with Lipofectamine 3000 served as negative control

Glutathione, known as the master antioxidant, helps neutralize free radicals, supports liver function, and contributes to overall cellular health

4b, c and Supplementary Fig

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Since the concentration of NADPH in resting Ms is in the micromolar range (33), which is within the range of the K m s of NADPH-dependent enzymes, such as NOS2 (33), NOXes (56), glutathione reductase (57), small changes in intracellular NADPH abundance will greatly impact the activity of these enzymes (58)

The pancreas also releases bicarbonate to protect the gut from acid