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doi: 10.1530/EJE-07-0271 36 FeolaTCozzolinoASimonelliISbardellaEPozzaCGianettaEet al

Here is an example of one study done in adolescents

The selectivity is documented in the foundational paper: a peer-reviewed European Journal of Endocrinology study demonstrating that Ipamorelin stimulates growth hormone selectively without elevating ACTH, cortisol, or prolactin, which is exactly why it has become the default selective secretagogue in modern peptide medicine

This has led researchers to investigate a possible association with premature graying

Working with a registered dietitian to ensure nutrient-dense food choices within reduced caloric intake can help prevent deficiency-related brain fog