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8 When GLP-1 receptors are activated, they promote insulin release and decrease glucagon secretion in response to glucose levels

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What were finally recognizing is that obesity and weight struggles are very multifactorial, Hughes said

Prof Alexander Miras, an obesity expert at Ulster University who was not involved in the work, described the findings as very important, noting that while GLP-1s had been associated with improved functionality meaning it was easier to carry out everyday activities they had also been associated with a loss in muscle mass and strength

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